Plumbagin Ameliorates Diabetic Nephropathy via Interruption of Pathways that Include NOX4 Signalling

NADPH oxidase 4 (Nox4) is reported to be the major source of reactive oxygen species (ROS) in the kidneys during the early stages of diabetic nephropathy. It has been shown to mediate TGFβ1-induced differentiation of cardiac fibroblasts into myofibroblasts. Despite TGFβ1 being recognised as a mediat...

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Detalles Bibliográficos
Autores principales: Yong, Rachel, Chen, Xin-Ming, Shen, Sylvie, Vijayaraj, Swarna, Ma, Qing, Pollock, Carol A., Saad, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753271/
https://www.ncbi.nlm.nih.gov/pubmed/23991195
http://dx.doi.org/10.1371/journal.pone.0073428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753271/
https://www.ncbi.nlm.nih.gov/pubmed/23991195
http://dx.doi.org/10.1371/journal.pone.0073428

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