IL-4 Attenuates Th1-Associated Chemokine Expression and Th1 Trafficking to Inflamed Tissues and Limits Pathogen Clearance

Interleukin 4 (IL-4) plays a central role in the orchestration of Type 2 immunity. During T cell activation in the lymph node, IL-4 promotes Th2 differentiation and inhibits Th1 generation. In the inflamed tissue, IL-4 signals promote innate and adaptive Type-2 immune recruitment and effector functi...

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Detalles Bibliográficos
Autores principales: Lazarski, Christopher A., Ford, Jill, Katzman, Shoshana D., Rosenberg, Alexander F., Fowell, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753298/
https://www.ncbi.nlm.nih.gov/pubmed/23991011
http://dx.doi.org/10.1371/journal.pone.0071949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753298/
https://www.ncbi.nlm.nih.gov/pubmed/23991011
http://dx.doi.org/10.1371/journal.pone.0071949

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