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Breakpoint Features of Genomic Rearrangements in Neuroblastoma with Unbalanced Translocations and Chromothripsis

Neuroblastoma is a pediatric cancer of the peripheral nervous system in which structural chromosome aberrations are emblematic of aggressive tumors. In this study, we performed an in-depth analysis of somatic rearrangements in two neuroblastoma cell lines and two primary tumors using paired-end sequ...

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Detalles Bibliográficos
Autores principales: Boeva, Valentina, Jouannet, Stéphanie, Daveau, Romain, Combaret, Valérie, Pierre-Eugène, Cécile, Cazes, Alex, Louis-Brennetot, Caroline, Schleiermacher, Gudrun, Ferrand, Sandrine, Pierron, Gaëlle, Lermine, Alban, Frio, Thomas Rio, Raynal, Virginie, Vassal, Gilles, Barillot, Emmanuel, Delattre, Olivier, Janoueix-Lerosey, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753337/
https://www.ncbi.nlm.nih.gov/pubmed/23991058
http://dx.doi.org/10.1371/journal.pone.0072182