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The Role of Chromosome Missegregation in Cancer Development: A Theoretical Approach Using Agent-Based Modelling
Many cancers are aneuploid. However, the precise role that chromosomal instability plays in the development of cancer and in the response of tumours to treatment is still hotly debated. Here, to explore this question from a theoretical standpoint we have developed an agent-based model of tissue home...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753339/ https://www.ncbi.nlm.nih.gov/pubmed/23991060 http://dx.doi.org/10.1371/journal.pone.0072206 |