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TNF-Like Weak Inducer of Apoptosis (TWEAK) Promotes Beta Cell Neogenesis from Pancreatic Ductal Epithelium in Adult Mice

AIM/HYPOTHESIS: The adult mammalian pancreas has limited ability to regenerate in order to restore adequate insulin production from multipotent progenitors, the identity and function of which remain poorly understood. Here we test whether the TNF family member TWEAK (TNF-like weak inducer of apoptos...

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Detalles Bibliográficos
Autores principales: Wu, Fei, Guo, Lili, Jakubowski, Aniela, Su, Lihe, Li, Wan-Chun, Bonner-Weir, Susan, Burkly, Linda C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753348/
https://www.ncbi.nlm.nih.gov/pubmed/23991053
http://dx.doi.org/10.1371/journal.pone.0072132