Molten Globule of Hemoglobin Proceeds into Aggregates and Advanced Glycated End Products

Conformational alterations of bovine hemoglobin (Hb) upon sequential addition of glyoxal over a range of 0–90% v/v were investigated. At 20% v/v glyoxal, molten globule (MG) state of Hb was observed by altered tryptophan fluorescence, high ANS binding, existence of intact heme, native-like secondary...

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Detalles Bibliográficos
Autores principales: Iram, Afshin, Alam, Tauqeer, Khan, Javed M., Khan, Taqi A., Khan, Rizwan H., Naeem, Aabgeena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753358/
https://www.ncbi.nlm.nih.gov/pubmed/23991043
http://dx.doi.org/10.1371/journal.pone.0072075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753358/
https://www.ncbi.nlm.nih.gov/pubmed/23991043
http://dx.doi.org/10.1371/journal.pone.0072075

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