Alternative mRNA Splicing from the Glial Fibrillary Acidic Protein (GFAP) Gene Generates Isoforms with Distinct Subcellular mRNA Localization Patterns in Astrocytes

The intermediate filament network of astrocytes includes Glial fibrillary acidic protein (Gfap) as a major component. Gfap mRNA is alternatively spliced resulting in generation of different protein isoforms where Gfapα is the most predominant isoform. The Gfapδ isoform is expressed in proliferating...

Descripción completa

Detalles Bibliográficos
Autores principales: Thomsen, Rune, Daugaard, Tina F., Holm, Ida E., Nielsen, Anders Lade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753360/
https://www.ncbi.nlm.nih.gov/pubmed/23991052
http://dx.doi.org/10.1371/journal.pone.0072110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753360/
https://www.ncbi.nlm.nih.gov/pubmed/23991052
http://dx.doi.org/10.1371/journal.pone.0072110

Ejemplares similares