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Epigenetic control of Epstein–Barr virus transcription – relevance to viral life cycle?
DNA methylation normally leads to silencing of gene expression but Epstein–Barr virus (EBV) provides an exception to the epigenetic paradigm. DNA methylation is absolutely required for the expression of many viral genes. Although the viral genome is initially un-methylated in newly infected cells, i...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753449/ https://www.ncbi.nlm.nih.gov/pubmed/23986773 http://dx.doi.org/10.3389/fgene.2013.00161 |