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IL-6 pathway-driven investigation of response to IL-6 receptor inhibition in rheumatoid arthritis

OBJECTIVES: To determine whether heterogeneity in interleukin-6 (IL-6), IL-6 receptor and other components of the IL-6 signalling pathway/network, at the gene, transcript and protein levels, correlate with disease activity in patients with rheumatoid arthritis (RA) and with clinical response to toci...

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Detalles Bibliográficos
Autores principales: Wang, Jianmei, Platt, Adam, Upmanyu, Ruchi, Germer, Søren, Lei, Guiyuan, Rabe, Christina, Benayed, Ryma, Kenwright, Andrew, Hemmings, Andrew, Martin, Mitchell, Harari, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753518/
https://www.ncbi.nlm.nih.gov/pubmed/23959753
http://dx.doi.org/10.1136/bmjopen-2013-003199