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Prediction of site-specific interactions in antibody-antigen complexes: the proABC method and server

Motivation: Antibodies or immunoglobulins are proteins of paramount importance in the immune system. They are extremely relevant as diagnostic, biotechnological and therapeutic tools. Their modular structure makes it easy to re-engineer them for specific purposes. Short of undergoing a trial and err...

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Detalles Bibliográficos
Autores principales: Olimpieri, Pier Paolo, Chailyan, Anna, Tramontano, Anna, Marcatili, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753563/
https://www.ncbi.nlm.nih.gov/pubmed/23803466
http://dx.doi.org/10.1093/bioinformatics/btt369