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A comparative analysis of algorithms for somatic SNV detection in cancer

Motivation: With the advent of relatively affordable high-throughput technologies, DNA sequencing of cancers is now common practice in cancer research projects and will be increasingly used in clinical practice to inform diagnosis and treatment. Somatic (cancer-only) single nucleotide variants (SNVs...

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Detalles Bibliográficos
Autores principales: Roberts, Nicola D., Kortschak, R. Daniel, Parker, Wendy T., Schreiber, Andreas W., Branford, Susan, Scott, Hamish S., Glonek, Garique, Adelson, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753564/
https://www.ncbi.nlm.nih.gov/pubmed/23842810
http://dx.doi.org/10.1093/bioinformatics/btt375