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Subdiffusion Supports Joining Of Correct Ends During Repair Of DNA Double-Strand Breaks
The mobility of damaged chromatin regions in the nucleus may affect the probability of mis-repair. In this work, live-cell observation and distance tracking of GFP-tagged DNA damage response protein MDC1 was used to study the random-walk behaviour of chromatin domains containing radiation-induced DN...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753591/ https://www.ncbi.nlm.nih.gov/pubmed/23979012 http://dx.doi.org/10.1038/srep02511 |