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Subdiffusion Supports Joining Of Correct Ends During Repair Of DNA Double-Strand Breaks

The mobility of damaged chromatin regions in the nucleus may affect the probability of mis-repair. In this work, live-cell observation and distance tracking of GFP-tagged DNA damage response protein MDC1 was used to study the random-walk behaviour of chromatin domains containing radiation-induced DN...

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Detalles Bibliográficos
Autores principales:	Girst, S., Hable, V., Drexler, G. A., Greubel, C., Siebenwirth, C., Haum, M., Friedl, A. A., Dollinger, G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753591/ https://www.ncbi.nlm.nih.gov/pubmed/23979012 http://dx.doi.org/10.1038/srep02511

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