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Q/R site interactions with the M3 helix in GluK2 kainate receptor channels revealed by thermodynamic mutant cycles

RNA editing at the Q/R site near the apex of the pore loop of AMPA and kainate receptors controls a diverse array of channel properties, including ion selectivity and unitary conductance and susceptibility to inhibition by polyamines and cis-unsaturated fatty acids, as well as subunit assembly into...

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Detalles Bibliográficos
Autores principales: Lopez, Melany N., Wilding, Timothy J., Huettner, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753602/
https://www.ncbi.nlm.nih.gov/pubmed/23940260
http://dx.doi.org/10.1085/jgp.201311000