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Interactions among DIV voltage-sensor movement, fast inactivation, and resurgent Na current induced by the Na(V)β4 open-channel blocking peptide

Resurgent Na current flows as voltage-gated Na channels recover through open states from block by an endogenous open-channel blocking protein, such as the Na(V)β4 subunit. The open-channel blocker and fast-inactivation gate apparently compete directly, as slowing the onset of fast inactivation incre...

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Detalles Bibliográficos
Autores principales: Lewis, Amanda H., Raman, Indira M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753608/
https://www.ncbi.nlm.nih.gov/pubmed/23940261
http://dx.doi.org/10.1085/jgp.201310984