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Simultaneous knockout of Slo3 and CatSper1 abolishes all alkalization- and voltage-activated current in mouse spermatozoa

During passage through the female reproductive tract, mammalian sperm undergo a maturation process termed capacitation that renders sperm competent to produce fertilization. Capacitation involves a sequence of changes in biochemical and electrical properties, the onset of a hyperactivated swimming b...

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Detalles Bibliográficos
Autores principales: Zeng, Xu-Hui, Navarro, Betsy, Xia, Xiao-Ming, Clapham, David E., Lingle, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753610/
https://www.ncbi.nlm.nih.gov/pubmed/23980198
http://dx.doi.org/10.1085/jgp.201311011