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Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicity

Base excision repair (BER) and mismatch repair (MMR) pathways play an important role in modulating cis-Diamminedichloroplatinum (II) (cisplatin) cytotoxicity. In this article, we identified a novel mechanistic role of both BER and MMR pathways in mediating cellular responses to cisplatin treatment....

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Detalles Bibliográficos
Autores principales: Kothandapani, Anbarasi, Sawant, Akshada, Dangeti, Venkata Srinivas Mohan Nimai, Sobol, Robert W., Patrick, Steve M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753620/
https://www.ncbi.nlm.nih.gov/pubmed/23761438
http://dx.doi.org/10.1093/nar/gkt479