DNA phosphate crowding correlates with protein cationic side chain density and helical curvature in protein/DNA crystal structures

Sequence-specific binding of proteins to their DNA targets involves a complex spectrum of processes that often induce DNA conformational variation in the bound complex. The forces imposed by protein binding that cause the helical deformations are intimately interrelated and difficult to parse or ran...

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Detalles Bibliográficos
Autores principales: Grant, Bryce N., Dourlain, Elizabeth M., Araneda, Jayme N., Throneberry, Madison L., McFail-Isom, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753625/
https://www.ncbi.nlm.nih.gov/pubmed/23748560
http://dx.doi.org/10.1093/nar/gkt492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753625/
https://www.ncbi.nlm.nih.gov/pubmed/23748560
http://dx.doi.org/10.1093/nar/gkt492

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