Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells

The effects of diverse stresses on promoter selectivity and transcription regulation by the tumor suppressor p53 are poorly understood. We have taken a comprehensive approach to characterizing the human p53 network that includes p53 levels, binding, expression and chromatin changes under diverse str...

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Detalles Bibliográficos
Autores principales: Menendez, Daniel, Nguyen, Thuy-Ai, Freudenberg, Johannes M., Mathew, Viju J., Anderson, Carl W., Jothi, Raja, Resnick, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753631/
https://www.ncbi.nlm.nih.gov/pubmed/23775793
http://dx.doi.org/10.1093/nar/gkt504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753631/
https://www.ncbi.nlm.nih.gov/pubmed/23775793
http://dx.doi.org/10.1093/nar/gkt504

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