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Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells
The effects of diverse stresses on promoter selectivity and transcription regulation by the tumor suppressor p53 are poorly understood. We have taken a comprehensive approach to characterizing the human p53 network that includes p53 levels, binding, expression and chromatin changes under diverse str...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753631/ https://www.ncbi.nlm.nih.gov/pubmed/23775793 http://dx.doi.org/10.1093/nar/gkt504 |