Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition

LINE1s occupy 17% of the human genome and are its only active autonomous mobile DNA. L1s are also responsible for genomic insertion of processed pseudogenes and >1 million non-autonomous retrotransposons (Alus and SVAs). These elements have significant effects on gene organization and expression....

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Detalles Bibliográficos
Autores principales: Goodier, John L., Cheung, Ling E., Kazazian, Haig H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753637/
https://www.ncbi.nlm.nih.gov/pubmed/23749060
http://dx.doi.org/10.1093/nar/gkt512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753637/
https://www.ncbi.nlm.nih.gov/pubmed/23749060
http://dx.doi.org/10.1093/nar/gkt512

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