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Integrated analysis of microRNA and mRNA expression: adding biological significance to microRNA target predictions

Current microRNA target predictions are based on sequence information and empirically derived rules but do not make use of the expression of microRNAs and their targets. This study aimed to improve microRNA target predictions in a given biological context, using in silico predictions, microRNA and m...

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Detalles Bibliográficos
Autores principales: van Iterson, Maarten, Bervoets, Sander, de Meijer, Emile J., Buermans, Henk P., ’t Hoen, Peter A. C., Menezes, Renée X., Boer, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753644/
https://www.ncbi.nlm.nih.gov/pubmed/23771142
http://dx.doi.org/10.1093/nar/gkt525