Visualization of multivalent histone modification in a single cell reveals highly concerted epigenetic changes on differentiation of embryonic stem cells

Combinations of histone modifications have significant biological roles, such as maintenance of pluripotency and cancer development, but cannot be analyzed at the single cell level. Here, we visualized a combination of histone modifications by applying the in situ proximity ligation assay, which det...

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Detalles Bibliográficos
Autores principales: Hattori, Naoko, Niwa, Tohru, Kimura, Kana, Helin, Kristian, Ushijima, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753646/
https://www.ncbi.nlm.nih.gov/pubmed/23761442
http://dx.doi.org/10.1093/nar/gkt528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753646/
https://www.ncbi.nlm.nih.gov/pubmed/23761442
http://dx.doi.org/10.1093/nar/gkt528

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