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Rapid oligonucleotide-templated fluorogenic tetrazine ligations

Template driven chemical ligation of fluorogenic probes represents a powerful method for DNA and RNA detection and imaging. Unfortunately, previous techniques have been hampered by requiring chemistry with sluggish kinetics and background side reactions. We have developed fluorescent DNA probes cont...

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Detalles Bibliográficos
Autores principales: Šečkutė, Jolita, Yang, Jun, Devaraj, Neal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753649/
https://www.ncbi.nlm.nih.gov/pubmed/23775794
http://dx.doi.org/10.1093/nar/gkt540