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Peripheral and Thymic Foxp3(+) Regulatory T Cells in Search of Origin, Distinction, and Function

Over the past decade, much has been learnt and much more to discover about Foxp3(+) regulatory T cells (Tregs). Initially, it was thought that Tregs were a unique entity that originates in the thymus. It is now recognized that there is a fraternal twin sibling that is generated in the periphery. The...

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Detalles Bibliográficos
Autores principales: Dhamne, Chetan, Chung, Yeonseok, Alousi, Amin Majid, Cooper, Laurence J. N., Tran, Dat Quoc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753660/
https://www.ncbi.nlm.nih.gov/pubmed/23986762
http://dx.doi.org/10.3389/fimmu.2013.00253