Pronerve Growth Factor Induces Angiogenesis via Activation of TrkA: Possible Role in Proliferative Diabetic Retinopathy

Proliferative diabetic retinopathy (PDR) is the leading cause of blindness in working age Americans. We demonstrated that diabetes disturbs the homeostasis of nerve growth factor (NGF) resulting in accumulation of its precursor proNGF. Increases in proNGF were positively correlated with progression...

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Detalles Bibliográficos
Autores principales: Elshaer, Sally L., Abdelsaid, Mohammed A., Al-Azayzih, Ahmad, Kumar, Parag, Matragoon, Suraporn, Nussbaum, Julian J., El-Remessy, Azza B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753742/
https://www.ncbi.nlm.nih.gov/pubmed/23998130
http://dx.doi.org/10.1155/2013/432659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753742/
https://www.ncbi.nlm.nih.gov/pubmed/23998130
http://dx.doi.org/10.1155/2013/432659

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