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Andrographis paniculata Extract and Andrographolide Modulate the Hepatic Drug Metabolism System and Plasma Tolbutamide Concentrations in Rats

Andrographolide is the most abundant terpenoid of A. paniculata which is used in the treatment of diabetes. In this study, we investigated the effects of A. paniculata extract (APE) and andrographolide on the expression of drug-metabolizing enzymes in rat liver and determined whether modulation of t...

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Detalles Bibliográficos
Autores principales: Chen, Haw-Wen, Huang, Chin-Shiu, Liu, Pei-Fen, Li, Chien-Chun, Chen, Chiung-Tong, Liu, Cheng-Tzu, Chiang, Jia-Rong, Yao, Hsien-Tsung, Lii, Chong-Kuei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753754/
https://www.ncbi.nlm.nih.gov/pubmed/23997806
http://dx.doi.org/10.1155/2013/982689