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Andrographis paniculata Extract and Andrographolide Modulate the Hepatic Drug Metabolism System and Plasma Tolbutamide Concentrations in Rats
Andrographolide is the most abundant terpenoid of A. paniculata which is used in the treatment of diabetes. In this study, we investigated the effects of A. paniculata extract (APE) and andrographolide on the expression of drug-metabolizing enzymes in rat liver and determined whether modulation of t...
Autores principales: | Chen, Haw-Wen, Huang, Chin-Shiu, Liu, Pei-Fen, Li, Chien-Chun, Chen, Chiung-Tong, Liu, Cheng-Tzu, Chiang, Jia-Rong, Yao, Hsien-Tsung, Lii, Chong-Kuei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753754/ https://www.ncbi.nlm.nih.gov/pubmed/23997806 http://dx.doi.org/10.1155/2013/982689 |
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