Effects of Three Different Fibrates on Intrahepatic Cholestasis Experimentally Induced in Rats

Background. Activation of PPARα modulates cholesterol metabolism and suppresses bile acid synthesis. This study aims to evaluate the effect of PPARα agonists, fenofibrate, bezafibrate, and gemfibrozil, on acute cholestasis induced by ethinylestradiol (EE) plus chlorpromazine (CPZ) in rats. Method. 1...

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Detalles Bibliográficos
Autores principales: El-Sisi, Alaa, Hegazy, Sahar, El-Khateeb, Eman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753769/
https://www.ncbi.nlm.nih.gov/pubmed/23997763
http://dx.doi.org/10.1155/2013/781348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753769/
https://www.ncbi.nlm.nih.gov/pubmed/23997763
http://dx.doi.org/10.1155/2013/781348

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