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Translation of CGA codon repeats in yeast involves quality control components and ribosomal protein L1

Translation of CGA codon repeats in the yeast Saccharomyces cerevisiae is inefficient, resulting in dose-dependent reduction in expression and in production of an mRNA cleavage product, indicative of a stalled ribosome. Here, we use genetics and translation inhibitors to understand how ribosomes res...

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Detalles Bibliográficos
Autores principales: Letzring, Daniel P., Wolf, Andrew S., Brule, Christina E., Grayhack, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753928/
https://www.ncbi.nlm.nih.gov/pubmed/23825054
http://dx.doi.org/10.1261/rna.039446.113