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Long-term cultivation of colorectal carcinoma cells with anti-cancer drugs induces drug resistance and telomere elongation: an in vitro study

BACKGROUND: The role of telomerase activation in the expression and/or maintenance of drug resistance is not clearly understood. Therefore, we investigated the relationships, among the telomerase activity, telomere length and the expression of multidrug resistance genes in colorectal cancer cell lin...

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Detalles Bibliográficos
Autores principales: Kuranaga, Noritsugu, Shinomiya, Nariyoshi, Mochizuki, Hidetaka
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC37545/
https://www.ncbi.nlm.nih.gov/pubmed/11518543
http://dx.doi.org/10.1186/1471-2407-1-10