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Combined upregulation of matrix metalloproteinase-1 and proteinase-activated receptor-1 predicts unfavorable prognosis in human nasopharyngeal carcinoma

BACKGROUND: The upregulation of matrix metalloproteinase-1 (MMP-1) has been demonstrated to be correlated with lymph node metastasis of nasopharyngeal carcinoma (NPC), while the activation of protease-activated receptor-1 (PAR-1) mediates proliferation and invasion of NPC cells. The present study in...

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Detalles Bibliográficos
Autores principales: Yang, Rui, Xu, Yu, Li, Peizhong, Zhang, Xin, Wang, Junying, Gu, Dongsheng, Wang, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754819/
https://www.ncbi.nlm.nih.gov/pubmed/23986644
http://dx.doi.org/10.2147/OTT.S50389