Influence of the oncolytic parvovirus H-1, CTLA-4 antibody tremelimumab and cytostatic drugs on the human immune system in a human in vitro model of colorectal cancer cells

INTRODUCTION: Tumor-directed and immune-system-stimulating therapies are of special interest in cancer treatment. Here, we demonstrate the potential of parvovirus H-1 (H-1PV) to efficiently kill colorectal cancer cells and induce immunogenicity of colorectal tumors by inducing maturation of dendriti...

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Detalles Bibliográficos
Autores principales: Heinrich, Bernd, Goepfert, Katrin, Delic, Maike, Galle, Peter R, Moehler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754820/
https://www.ncbi.nlm.nih.gov/pubmed/23986643
http://dx.doi.org/10.2147/OTT.S49371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754820/
https://www.ncbi.nlm.nih.gov/pubmed/23986643
http://dx.doi.org/10.2147/OTT.S49371

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