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A role for gut-associated lymphoid tissue in shaping the human B cell repertoire

We have tracked the fate of immature human B cells at a critical stage in their development when the mature B cell repertoire is shaped. We show that a major subset of bone marrow emigrant immature human B cells, the transitional 2 (T2) B cells, homes to gut-associated lymphoid tissue (GALT) and tha...

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Detalles Bibliográficos
Autores principales: Vossenkämper, Anna, Blair, Paul A., Safinia, Niloufar, Fraser, Louise D., Das, Lisa, Sanders, Theodore J., Stagg, Andrew J., Sanderson, Jeremy D., Taylor, Kirstin, Chang, Fuju, Choong, Lee M., D’Cruz, David P., MacDonald, Thomas T., Lombardi, Giovanna, Spencer, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754866/
https://www.ncbi.nlm.nih.gov/pubmed/23940259
http://dx.doi.org/10.1084/jem.20122465