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A role for gut-associated lymphoid tissue in shaping the human B cell repertoire
We have tracked the fate of immature human B cells at a critical stage in their development when the mature B cell repertoire is shaped. We show that a major subset of bone marrow emigrant immature human B cells, the transitional 2 (T2) B cells, homes to gut-associated lymphoid tissue (GALT) and tha...
Autores principales: | Vossenkämper, Anna, Blair, Paul A., Safinia, Niloufar, Fraser, Louise D., Das, Lisa, Sanders, Theodore J., Stagg, Andrew J., Sanderson, Jeremy D., Taylor, Kirstin, Chang, Fuju, Choong, Lee M., D’Cruz, David P., MacDonald, Thomas T., Lombardi, Giovanna, Spencer, Jo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754866/ https://www.ncbi.nlm.nih.gov/pubmed/23940259 http://dx.doi.org/10.1084/jem.20122465 |
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