Cargando…

The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2

Osteoblasts are responsible for the formation and mineralization of the skeleton. To identify novel regulators of osteoblast differentiation, we conducted an unbiased forward genetic screen using a lentiviral-based shRNA library. This functional genomics analysis led to the identification of the mic...

Descripción completa

Detalles Bibliográficos
Autores principales: Zou, Weiguo, Greenblatt, Matthew B., Brady, Nicholas, Lotinun, Sutada, Zhai, Bo, de Rivera, Heather, Singh, Anju, Sun, Jun, Gygi, Steven P., Baron, Roland, Glimcher, Laurie H., Jones, Dallas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754873/
https://www.ncbi.nlm.nih.gov/pubmed/23918955
http://dx.doi.org/10.1084/jem.20111790