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Formation of a Unique Cluster of G-Quadruplex Structures in the HIV-1 nef Coding Region: Implications for Antiviral Activity

G-quadruplexes are tetraplex structures of nucleic acids that can form in G-rich sequences. Their presence and functional role have been established in telomeres, oncogene promoters and coding regions of the human chromosome. In particular, they have been proposed to be directly involved in gene reg...

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Detalles Bibliográficos
Autores principales: Perrone, Rosalba, Nadai, Matteo, Poe, Jerrod A., Frasson, Ilaria, Palumbo, Manlio, Palù, Giorgio, Smithgall, Thomas E., Richter, Sara N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754912/
https://www.ncbi.nlm.nih.gov/pubmed/24015290
http://dx.doi.org/10.1371/journal.pone.0073121