Ongoing Contact Activation in Patients with Hereditary Angioedema

Hereditary angioedema (HAE) is predominantly caused by a deficiency in C1 esterase inhibitor (C1INH) (HAE-C1INH). C1INH inhibits activated factor XII (FXIIa), activated factor XI (FXIa), and kallikrein. In HAE-C1INH patients the thrombotic risk is not increased even though activation of the contact...

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Detalles Bibliográficos
Autores principales: Konings, Joke, Cugno, Massimo, Suffritti, Chiara, ten Cate, Hugo, Cicardi, Marco, Govers-Riemslag, José W. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754953/
https://www.ncbi.nlm.nih.gov/pubmed/24013493
http://dx.doi.org/10.1371/journal.pone.0074043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754953/
https://www.ncbi.nlm.nih.gov/pubmed/24013493
http://dx.doi.org/10.1371/journal.pone.0074043

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