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Iron Binding at Specific Sites within the Octameric HbpS Protects Streptomycetes from Iron-Mediated Oxidative Stress

The soil bacterium Streptomyces reticuli secretes the octameric protein HbpS that acts as a sensory component of the redox-signalling pathway HbpS-SenS-SenR. This system modulates a genetic response on iron- and haem-mediated oxidative stress. Moreover, HbpS alone provides this bacterium with a defe...

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Detalles Bibliográficos
Autores principales: Wedderhoff, Ina, Kursula, Inari, Groves, Matthew R., Ortiz de Orué Lucana, Darío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754957/
https://www.ncbi.nlm.nih.gov/pubmed/24013686
http://dx.doi.org/10.1371/journal.pone.0071579