Examination of Artificial MiRNA Mimics with Centered–Site Complementarity for Gene Targeting

BACKGROUND: MiRNA primarily acts to repress gene expression at the post-transcriptional level through imperfect complementarity of its 5′ region to the “seed site” in the 3′ untranslated region of target mRNAs, with its “3′–supplementary site” and “center site” also playing important roles under cer...

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Detalles Bibliográficos
Autores principales: Zhang, Shu-Guang, Liu, Chun-Yan, Li, Li, Sun, Tong-Wen, Luo, Yong-Gang, Yun, Wen-Jing, Zhang, Jin-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754971/
https://www.ncbi.nlm.nih.gov/pubmed/24013456
http://dx.doi.org/10.1371/journal.pone.0072062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754971/
https://www.ncbi.nlm.nih.gov/pubmed/24013456
http://dx.doi.org/10.1371/journal.pone.0072062

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