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Locking the 150-Cavity Open: In Silico Design and Verification of Influenza Neuraminidase Inhibitors
Neuraminidase (NA) of influenza is a key target for virus infection control and the recently discovered open 150-cavity in group-1 NA provides new opportunity for novel inhibitors design. In this study, we used a combination of theoretical methods including fragment docking, molecular linking and mo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755005/ https://www.ncbi.nlm.nih.gov/pubmed/24015302 http://dx.doi.org/10.1371/journal.pone.0073344 |