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Real-time estimation of biomass and specific growth rate in physiologically variable recombinant fed-batch processes
The real-time measurement of biomass has been addressed since many years. The quantification of biomass in the induction phase of a recombinant bioprocess is not straight forward, since biological burden, caused by protein expression, can have a significant impact on the cell morphology and physiolo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755222/ https://www.ncbi.nlm.nih.gov/pubmed/23178981 http://dx.doi.org/10.1007/s00449-012-0848-4 |