Synergy between chemotherapeutic agents and CTLA-4 blockade in preclinical tumor models

Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) binding agent, has proven to be an effective monotherapy for metastatic melanoma and has shown antitumor activity in trials when administered with other therapeutic agents. We hypothesized that the combination of ipilimumab with chemotherapeuti...

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Detalles Bibliográficos
Autores principales: Jure-Kunkel, Maria, Masters, Gregg, Girit, Emel, Dito, Gennaro, Lee, Francis, Hunt, John T., Humphrey, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755230/
https://www.ncbi.nlm.nih.gov/pubmed/23873089
http://dx.doi.org/10.1007/s00262-013-1451-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755230/
https://www.ncbi.nlm.nih.gov/pubmed/23873089
http://dx.doi.org/10.1007/s00262-013-1451-5

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