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T-cell immunosenescence: lessons learned from mouse models of aging

It is well established that increasing age is associated with a decreased capacity of the immune system to mediate effective immune responses to vaccination and invading pathogens. Because of the inherent limitations of conducting experiments in humans, much of what we have learned is owed to the ut...

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Detalles Bibliográficos
Autores principales: Maue, Alexander C., Yager, Eric J., Swain, Susan L., Woodland, David L., Blackman, Marcia A., Haynes, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755270/
https://www.ncbi.nlm.nih.gov/pubmed/19541537
http://dx.doi.org/10.1016/j.it.2009.04.007