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T-cell immunosenescence: lessons learned from mouse models of aging
It is well established that increasing age is associated with a decreased capacity of the immune system to mediate effective immune responses to vaccination and invading pathogens. Because of the inherent limitations of conducting experiments in humans, much of what we have learned is owed to the ut...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755270/ https://www.ncbi.nlm.nih.gov/pubmed/19541537 http://dx.doi.org/10.1016/j.it.2009.04.007 |