Structural basis for ribosomal 16S rRNA cleavage by the cytotoxic domain of colicin E3

The toxin colicin E3 targets the 30S subunit of bacterial ribosomes and cleaves a phosphodiester bond in the decoding center. We present the crystal structure of the 70S ribosome in complex with the cytotoxic domain of colicin E3 (E3-rRNase). The structure reveals how the rRNase domain of colicin bi...

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Detalles Bibliográficos
Autores principales: Ng, C Leong, Lang, Kathrin, Meenan, Nicola AG, Sharma, Amit, Kelley, Ann C, Kleanthous, Colin, Ramakrishnan, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755339/
https://www.ncbi.nlm.nih.gov/pubmed/20852642
http://dx.doi.org/10.1038/nsmb.1896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755339/
https://www.ncbi.nlm.nih.gov/pubmed/20852642
http://dx.doi.org/10.1038/nsmb.1896

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