Patient-specific iPSC-derived photoreceptor precursor cells as a means to investigate retinitis pigmentosa

Next-generation and Sanger sequencing were combined to identify disease-causing USH2A mutations in an adult patient with autosomal recessive RP. Induced pluripotent stem cells (iPSCs), generated from the patient’s keratinocytes, were differentiated into multi-layer eyecup-like structures with featur...

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Detalles Bibliográficos
Autores principales: Tucker, Budd A, Mullins, Robert F, Streb, Luan M, Anfinson, Kristin, Eyestone, Mari E, Kaalberg, Emily, Riker, Megan J, Drack, Arlene V, Braun, Terry A, Stone, Edwin M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755341/
https://www.ncbi.nlm.nih.gov/pubmed/23991284
http://dx.doi.org/10.7554/eLife.00824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755341/
https://www.ncbi.nlm.nih.gov/pubmed/23991284
http://dx.doi.org/10.7554/eLife.00824

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