Disrupting malaria parasite AMA1 – RON2 interaction with a small molecule prevents erythrocyte invasion

Plasmodium falciparumresistance to artemisinin derivatives, the first-line anti-malarial drug, drives the search for new classes of chemotherapeutic agents. Current discovery is primarily directed against the intracellular forms of the parasite. However, late schizont-infected red blood cells (RBCs)...

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Detalles Bibliográficos
Autores principales: Srinivasan, Prakash, Yasgar, Adam, Luci, Diane K., Beatty, Wandy L., Hu, Xin, Andersen, John, Narum, David L., Moch, J. Kathleen, Sun, Hongmao, Haynes, J. David, Maloney, David J., Jadhav, Ajit, Simeonov, Anton, Miller, Louis H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755449/
https://www.ncbi.nlm.nih.gov/pubmed/23907321
http://dx.doi.org/10.1038/ncomms3261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755449/
https://www.ncbi.nlm.nih.gov/pubmed/23907321
http://dx.doi.org/10.1038/ncomms3261

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