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Maternal Loss of miRNAs Leads to Increased Variance in Primordial Germ Cell Numbers in Drosophila melanogaster

MicroRNAs (miRNAs) are posttranscriptional regulators of gene expression that may act as buffering agents to stabilize gene-regulatory networks. Here, we identify two miRNAs that are maternally required for normal embryonic primordial germ cell development in Drosophila melanogaster. Embryos derived...

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Detalles Bibliográficos
Autores principales: Kugler, Jan-Michael, Chen, Ya-Wen, Weng, Ruifen, Cohen, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755917/
https://www.ncbi.nlm.nih.gov/pubmed/23893743
http://dx.doi.org/10.1534/g3.113.007591