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A Second Tubulin Binding Site on the Kinesin-13 Motor Head Domain Is Important during Mitosis

Kinesin-13s are microtubule (MT) depolymerases different from most other kinesins that move along MTs. Like other kinesins, they have a motor or head domain (HD) containing a tubulin and an ATP binding site. Interestingly, kinesin-13s have an additional binding site (Kin-Tub-2) on the opposite side...

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Detalles Bibliográficos
Autores principales: Zhang, Dong, Asenjo, Ana B., Greenbaum, Michaela, Xie, Luping, Sharp, David J., Sosa, Hernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755979/
https://www.ncbi.nlm.nih.gov/pubmed/24015286
http://dx.doi.org/10.1371/journal.pone.0073075