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Sulfated Escherichia coli K5 Polysaccharide Derivatives Inhibit Dengue Virus Infection of Human Microvascular Endothelial Cells by Interacting with the Viral Envelope Protein E Domain III

Dengue virus (DENV) is an emerging mosquito-borne pathogen that causes cytokine-mediated alterations in the barrier function of the microvascular endothelium, leading to dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). We observed that DENV (serotype 2) productively infects primary (H...

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Detalles Bibliográficos
Autores principales: Vervaeke, Peter, Alen, Marijke, Noppen, Sam, Schols, Dominique, Oreste, Pasqua, Liekens, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755990/
https://www.ncbi.nlm.nih.gov/pubmed/24015314
http://dx.doi.org/10.1371/journal.pone.0074035